发明名称 |
PACKAGED VIRUS-LIKE PARTICLES |
摘要 |
<p>The present invention is related to the fields of vaccinology, immunology and medicine. The invention provides compositions and methods for enhancing immunological responses against antigens coupled or fused to virus-like particles (VLPs) packaged with immunostimulatory nucleic acids, preferably oligonucleotides containing at least one non-methylated CpG sequence and a toll-like receptor (TLR) ligand. The invention can be used to induce strong antibody and T cell responses particularly useful for the treatment of allergies, tumors and chronic viral diseases as well as other chronic diseases.</p> |
申请公布号 |
WO2005004907(A1) |
申请公布日期 |
2005.01.20 |
申请号 |
WO2004EP07679 |
申请日期 |
2004.07.12 |
申请人 |
CYTOS BIOTECHNOLOGY AG;BACHMANN, MARTIN, F.;SCHWARZ, KATRIN |
发明人 |
BACHMANN, MARTIN, F.;SCHWARZ, KATRIN |
分类号 |
A61K39/002;A61K39/02;A61K39/12;A61K39/29;A61K39/35;A61K39/39;A61P37/04;C07K14/02;C07K14/025;C07K14/08;C12N7/04;C12N15/12;(IPC1-7):A61K39/00;A61K39/36;A61K39/295 |
主分类号 |
A61K39/002 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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