| 发明名称 |
MOUSE MONOCLONAL ANTI-IDIOTYPE ANTIBODY 11D10 AND USE THEREOF |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a new therapeutic approach to recurrent breast cancer which is untreatable by a standard treatment. <P>SOLUTION: Disclosed are mouse anti-idiotype antibody 11D10 capable of causing immune response to high molecular weight mucin of human milk fat globule (HMFG), polypeptides including at least one part of the variable region of anti-idiotype antibody 11D10 and a polynucleotide encoding these polypeptides, pharmaceutical compositions and vaccines including 11D10, 11D10 polypeptide and/or 11D10 polynucleotide, or diagnostic kits and methods using 11D10, 11D10 polypeptide and/or 11D10 polynucleotide. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p> |
| 申请公布号 |
JP2005013233(A) |
申请公布日期 |
2005.01.20 |
| 申请号 |
JP20040227291 |
申请日期 |
2004.08.03 |
| 申请人 |
UNIV OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
CHATTERJEE MALAYA;FOON KENNETH A;CHATTERJEE SUNIL K |
| 分类号 |
C12N15/02;A61K31/00;A61K31/70;A61K38/00;A61K39/00;A61K39/275;A61K39/39;A61K39/395;A61K48/00;A61P35/00;A61P37/00;A61P37/02;A61P37/04;C07K14/52;C07K16/42;C07K19/00;C12N5/10;C12N15/09;C12N15/13;C12P21/08;C12Q1/68;C12R1/91;G01N33/574;G01N33/577;(IPC1-7):C12N5/10 |
主分类号 |
C12N15/02 |
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