发明名称 |
METHOD FOR PHOTODYNAMIC INACTIVATION OF PATHOGENS USING ALA |
摘要 |
The invention relates to a method for inactivating pathogens, particularly viruses and bacteria in a biological fluid comprising blood cells. The method comprises the steps: preparation of, or placing of the fluid in a container, at least a part of the walls of which are transparent to radiation with a wavelength between 350 nm and 450 nm, introduction of the 5-aminolevulinic acid (ALA), or a derivative thereof into the fluid, such as to allow the transformation of the ALA into protoporphyrin IX, irradiation of the container with at least one radiation of wavelength between 350 nm and 450 nm such that, on activating the protoporphyrin IX, the pathogens are inactivated, whereby the fluid has the leukocytes removed prior to the introduction of the ALA. |
申请公布号 |
WO2005004862(A2) |
申请公布日期 |
2005.01.20 |
申请号 |
WO2004FR01805 |
申请日期 |
2004.07.08 |
申请人 |
MACO PHARMA;VIGNERON, CLAUDE;VERPOORT, THIERRY;MARCHAND-ARVIER, MONIQUE;NOTET, VERONIQUE;MAURICE-DUELLI, AURORE |
发明人 |
VIGNERON, CLAUDE;VERPOORT, THIERRY;MARCHAND-ARVIER, MONIQUE;NOTET, VERONIQUE;MAURICE-DUELLI, AURORE |
分类号 |
A61K31/195;A61K31/409;A61L2/00;A61L2/10;A61P7/02;A61P7/04 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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