| 摘要 |
<p>The present invention is concerned with a novel process for the manufacture of tocols and tocopherols, especially alphatocopherol, and cc-tocopheryl acetate by the reaction of a hydroquinone comprising 0 to 3 methyl groups, especially 2,3,5-trimethylhydroquinone, or 2,3,6-trimethylhydroquinone- 1 -acetate, respectively, with isophytol, phytol or a(n) (iso)phytol derivative, most preferably with isophytol, in the presence of bismuth trifluoromethanesulphonate, Bi(OS02CF3)3, as the catalyst in an organic solvent or a biphasic solvent system. A further object of the invention is the use of bismuth trifluoromethanesulphonate, Bi(OS02CF3)3, as the catalyst in Friedel-Crafts type alkylation reactions and ring-closure reactions in organic solvents.</p> |
