| 发明名称 |
ПЕПТИДНЫЕ СОЕДИНЕНИЯ |
| 摘要 |
The present invention relates to a compound of the formula (I) wherein R1 is benzofuranyl substituted by halogen, or styryl substituted by halogen; R2 is substituted hydroxy, substituted mercapto or substituted sulfonyl; and X is or pharmaceutically acceptable salts thereof. The compound (1) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NO-mediated diseases in human being and animals |
| 申请公布号 |
RU2003124057(A) |
申请公布日期 |
2005.01.20 |
| 申请号 |
RU20030124057 |
申请日期 |
2001.12.18 |
| 申请人 |
ФУДЗИСАВА ФАРМАСЬЮТИКАЛ КО.,ЛТД. (JP) |
发明人 |
СИМА Итиро (JP);ОХКАВА Такехико (JP);САТО Кентаро (JP);ИСИБАСИ Наоки (JP);ИМАМУРА Кенитиро (JP) |
| 分类号 |
A61K38/00;A61K31/436;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/14;A61P11/00;A61P11/06;A61P13/12;A61P15/00;A61P15/10;A61P17/00;A61P17/04;A61P19/02;A61P19/06;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/16;A61P25/28;A61P27/02;A61P27/06;A61P27/10;A61P27/12;A61P27/14;A61P29/00;A61P31/04;A61P31/12;A61P31/22;A61P35/00;A61P35/04;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K5/06;C07K5/078 |
主分类号 |
A61K38/00 |
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