发明名称 SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS
摘要 The present invention discloses a compound of formula (I): - wherein A is an aromatic moiety or selected from benzyl, C1-C16 alkyl dialkylamino, dialkylaminoalkyl, alkoxyalkyl, cyano, and mono-, di-, or tri-hydroxyalkyl and/or aryl, B is an aromatic moiety, R1 and R2 are independently C1 to C6 alkyl or NR1R2 forms a 5 to 8 membered ring optionally containing one or two additional heteroatoms selected from nitrogen, oxygen and sulphur and which is optionally substituted by C1 to C6 alkyl, and n is 0 or 1, and salts and hydrates thereof. The invention is also concerned with methods of synthesisi ng the compounds and their uses as 5-HT7 ligands.
申请公布号 CA2531787(A1) 申请公布日期 2005.01.20
申请号 CA20042531787 申请日期 2004.06.29
申请人 ASTON UNIVERSITY 发明人 FERNANDEZ, ISIDRO MERINO;LATTMANN, ERIC
分类号 C07D211/14;A61K31/445;A61P25/00;C07D295/13 主分类号 C07D211/14
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