发明名称 USE OF ANTITUMOR INDOLOPYRROLOCARBAZOLE DERIVATIVE AND OTHER ANTICANCER AGENT IN COMBINATION
摘要 This invention relates to a combined preparation for simultaneous, separate, or sequential administration in the treatment of cancer, comprising two separate preparations: a preparation comprising, in combination with a pharmaceutically acceptable carrier or diluent, at least one compound of general formula I: <CHEM> wherein R<1> and R<2> each independently represent a hydrogen atom, lower alkyl, or the like, and G represents pentosyl or the like, X<1> and X<2> each independently represent a hydrogen atom, a halogen atom, or the like or a pharmaceutically acceptable salt thereof; and a preparation, in combination with a pharmaceutically acceptable carrier or diluent, such as antitumor alkylating agents, antitumor antimetabolites, antitumor antibiotics, or plant-derived antitumor agents (a preparation comprising at least one compound of general formula I or a pharmaceutically acceptable salt thereof may be combined with two or more other antitumor agents), and a method for cancer treatment comprising the administration of these preparations in combination.
申请公布号 EP1498127(A1) 申请公布日期 2005.01.19
申请号 EP20020807108 申请日期 2002.09.30
申请人 BANYU PHARMACEUTICAL CO., LTD. 发明人 ARAKAWA,H.;MONDEN,Y.;NAKATSURU,Y.;KODERA,T.
分类号 A61K31/24;A61K31/282;A61K31/4745;A61K31/519;A61K31/704;A61K31/7048;A61K31/7056;A61K45/00;A61K45/06;A61P35/00;A61P43/00 主分类号 A61K31/24
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