METHODS AND COMPOUND MIXTURES FOR DETERMINING PROTEIN ACTIVITY USING NMR SPECTROSCOPY
摘要
<p>The invention relates to methods for determining protein activity using NMR spectroscopy. The present invention provides a method for determining protein activity in vivo using probe compounds and enhancing the nuclear polarisation of NMR active nuclei present in the probe compounds (hereinafter termed "hyperpolarisation") prior to NMR analysis. The invention also provides mixtures of probe compounds for the above-mentioned method.</p>
申请公布号
EP1497448(A1)
申请公布日期
2005.01.19
申请号
EP20030725890
申请日期
2003.04.15
申请人
GE HEALTHCARE AS
发明人
CLARKE, BILL;GOLMAN, KLAES;LERCHE, MATHILDE H.;LOOKER, MIKE;O'SULLIVAN, MIKE;SANTOS, ALBIE;SERVIN, ROLF;THANING, MIKKEL;ARDENKJAER-LARSEN, JAN HENRIK