| 发明名称 |
USE OF INTERLEUKIN-24 TO TREAT OVARIAN CANCER |
| 摘要 |
The present invention relates to the anti-cancer activity of IL-24 polypeptide molecules. IL-24 is a cytokine involved in inflammatory processes and human disease. The present invention includes Use of IL-24 for decreasing proliferation of ovarian cancer cells, treating ovarian cancer, amongst other uses disclosed. IL-24 polypeptides can be administered alone, or can be fused to cytotoxic moieties, and can be administered in conjunction with radiation or chemotherapeutic agents. |
| 申请公布号 |
EP1496925(A2) |
申请公布日期 |
2005.01.19 |
| 申请号 |
EP20030719612 |
申请日期 |
2003.04.08 |
| 申请人 |
ZYMOGENETICS, INC. |
发明人 |
CHANDRASEKHER, YASMIN, A.;MCKERNAN, PATRICIA, A. |
| 分类号 |
A61K38/00;C12N15/09;A61K31/282;A61K31/337;A61K31/4745;A61K31/53;A61K31/704;A61K31/7048;A61K31/7064;A61K33/24;A61K38/20;A61K41/00;A61K45/00;A61K47/48;A61P35/00;C07K14/54;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
