发明名称 TROPANE DERIVATIVES AS MODULATORS OF CCR5
摘要 The present invention provides compounds of formula (I) wherein, X, Y, R1, R2 and R2 are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HTV and genetically related retroviruses.
申请公布号 UA75534(C2) 申请公布日期 2005.01.17
申请号 UA20041008109 申请日期 2003.03.31
申请人 PFIZER INC. 发明人 BASFORD PATRICIA ANN;STEPHENSON PETER THOMAS;TAYLOR STEPHAN COLIN JOHN
分类号 A61K31/46;A61P1/04;A61P1/16;A61P1/18;A61P3/04;A61P3/10;A61P7/06;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P25/00;A61P25/02;A61P25/28;A61P27/16;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07D451/04;C07D519/00 主分类号 A61K31/46
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