COMPOSITION COMPRISING PROTOCATHECHUALDEHYDE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENTS FOR PREVENTION AND TREATMENT OF DIABETIC COMPLICATIONS

摘要

PURPOSE: Provided is a composition comprising protocathechualdehyde and its pharmaceutically acceptable salt as active ingredients. The protocathechualdehyde inhibits the generation of glycation end products and thus the composition is useful for prevention and treatment of diabetic complications. CONSTITUTION: The composition is characterized by comprising protocathechualdehyde and its pharmaceutically acceptable salt as active ingredients. The protocathechualdehyde inhibits the generation of glycation end products, reduces blood glucose level, prevents body weight loss, inhibits kidney hypertrophy, and reduces the numerical value of BUN, triglyceride and creatine significantly and the like and is thus useful for prevention and treatment of diabetic complications.