| 发明名称 |
CIS-imidazolines as MDM2 inhibitors |
| 摘要 |
<p>The present invention provides compound according to formula (I) and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.</p> |
| 申请公布号 |
AU2004253245(A1) |
申请公布日期 |
2005.01.13 |
| 申请号 |
AU20040253245 |
申请日期 |
2004.06.09 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
EMILY AIJUN LIU;BINH THANH VU;NADER FOTOUHI |
| 分类号 |
A61K31/4164;A61P35/00;C07D233/22;C07D401/06;C07D403/06 |
主分类号 |
A61K31/4164 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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