BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASES INHIBITORS
摘要
The invention provides compounds having activity as inhibitors of cyclin dependent kinases, glycogen synthase kinase-3 and Aurora kinases for use in the treatment of disease states and conditions such as cancer that are mediated by the kinases. The compounds have the general formula (I). Also included within formula (I) are the salts, solvates and N-oxides of the compounds.
申请公布号
CA2531050(A1)
申请公布日期
2005.01.13
申请号
CA20042531050
申请日期
2004.07.05
申请人
ASTEX THERAPEUTICS LIMITED
发明人
TREWARTHA, GARY;WYATT, PAUL;WOOLFORD, ALISON JO-ANNE;WOODHEAD, ANDREW JAMES;O'BRIEN, MICHAEL ALISTAIR;GILL, ADRIAN LIAM;EARLY, THERESA RACHEL;NAVARRO, EVA FIGUEROA;CARR, MARIA GRAZIA;HOWARD, STEVEN;BERDINI, VALERIO