| 发明名称 |
AGLYCOSYL ANTI-CD154 (CD40 LIGAND) ANTIBODIES AND USES THEREOF |
| 摘要 |
<p>The invention relates to aglycosyl anti-CD154 antibodies or antibody derivatives, characterized by a modification at the conserved N-linked site in the CH2 domains of the Fc portion of said antibody. The invention also relat es to the treatment of immune response related diseases and inhibition of unwanted immune response with such aglycosylated anti-CD154 antibodies or antibody derivatives thereof.</p> |
| 申请公布号 |
CA2528551(A1) |
申请公布日期 |
2005.01.13 |
| 申请号 |
CA20042528551 |
申请日期 |
2004.06.14 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
BURKLY, LINDA C.;BENJAMIN, CHRISTOPHER D.;TAYLOR, FREDERICK R.;GARBER, ELLEN A. |
| 分类号 |
C07K16/28;A61K39/395;C12N5/10 |
主分类号 |
C07K16/28 |
| 代理机构 |
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