发明名称 |
METHODS AND COMPOSITIONS FOR TREATING DISORDERS OF THE EXTRACELLULAR MATRIX |
摘要 |
The present invention provides a method for altering the level of an extracellular matrix (ECM) protein produced by a cell, the method including modulating expression or activity of a cell division auto antigen (CDA). The Applicants have surprisingly found that a CDA is involved in a pathway that controls the level of ECM protein produced by mammalian cells. The invention has relevance to a number of ECM-related disorders such as renal fibrosis an d atherosclerosis.
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申请公布号 |
CA2530866(A1) |
申请公布日期 |
2005.01.13 |
申请号 |
CA20042530866 |
申请日期 |
2004.06.30 |
申请人 |
BAKER MEDICAL RESEARCH INSTITUTE |
发明人 |
ZHONGLIN, CHAI |
分类号 |
A61K38/18;A01K67/027;A61P9/10;A61P13/12;A61P17/02;C07K14/47;G01N33/68 |
主分类号 |
A61K38/18 |
代理机构 |
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主权项 |
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地址 |
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