发明名称 Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
摘要 A method for inhibiting and/or ameliorating the occurrence of diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals in a subject whereby a subject is administered a carotenoid analog or derivative, either alone or in combination with another carotenoid analog or derivative, or co-antioxidant formulation. The analog or derivative is administered such that the subject's risk of experiencing diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals may be thereby reduced. The analog or analog combination may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include a chemical compound including an at least partially water soluble carotenoid analog or derivative. The carotenoid analog may include a conjugated polyene with between 7 to 14 double bonds. The conjugated polyene may include a cyclic ring including at least one substituent. In some embodiments, a cyclic ring of a carotenoid analog or derivative may include at least one substituent. The substituent may be coupled to the cyclic ring with an ether functionality.
申请公布号 US2005009758(A1) 申请公布日期 2005.01.13
申请号 US20040793671 申请日期 2004.03.04
申请人 LOCKWOOD SAMUEL FOURNIER;O'MALLEY SEAN;WATUMULL DAVID G.;HIX LAURA M.;JACKSON HENRY;NADOLSKI GEOFF 发明人 LOCKWOOD SAMUEL FOURNIER;O'MALLEY SEAN;WATUMULL DAVID G.;HIX LAURA M.;JACKSON HENRY;NADOLSKI GEOFF
分类号 A01N27/00;A61K31/01;A61K31/015;A61K31/045;A61K31/07;A61K31/075;A61K31/12;A61K31/13;A61K31/185;A61K31/215;A61K31/225;A61K31/255;A61K31/325;A61K31/401;A61K31/404;A61K31/4172;A61K31/535;A61K31/537;A61K31/66;A61K31/665;A61K31/70;A61K31/704;A61K31/715;C07D207/16;C07D233/60;C07D265/30;C07D307/58;C07F9/02;C07F9/117;C07H13/04;(IPC1-7):A61K31/704 主分类号 A01N27/00
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