| 发明名称 |
ANTIBODY RECOGNIZING PROLIFERATIVE HUMAN LIVER CELLS, PROLIFERATIVE HUMAN LIVER CELLS AND FUNCTIONAL HUMAN LIVER CELLS |
| 摘要 |
<p>The invention provides a monoclonal antibody which specifically recognizes proliferative human hepatocytes, a method for isolating proliferative human hepatocytes by using the antibody, and a method for inducing to differentiate the proliferative human hepatocytes to functional human hepatocytes. Further, the invention provides the proliferative human hepatocytes and functional human hepatocytes obtained by the methods, as well as a cell kit and a hybrid artificial liver comprising those hepatocytes.</p> |
| 申请公布号 |
EP1496066(A1) |
申请公布日期 |
2005.01.12 |
| 申请号 |
EP20030712923 |
申请日期 |
2003.03.25 |
| 申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY;HIROSHIMA INDUSTRIAL PROMOTION ORGANIZATION |
发明人 |
MUKAIDANI, CHISE;YOSHIZATO, KATSUTOSHI;YAMASAKI, CHIHIRO |
| 分类号 |
C07K16/18;C07K16/28;C12N5/071;C12P21/08;C12N5/18;(IPC1-7):C07K16/18;C12N15/09;A61L27/00;C12N5/08 |
主分类号 |
C07K16/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
