| 发明名称 |
Antitumoral analogs of ET-743 |
| 摘要 |
Antitumour compounds have the five membered fused ring ecteinascidin structure of the formula (XIV): <CHEM> The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or derivatised aminomethylene group or an optionally protected or derivatised hydroxymethylene group. |
| 申请公布号 |
EP1496060(A1) |
申请公布日期 |
2005.01.12 |
| 申请号 |
EP20040010399 |
申请日期 |
2001.05.15 |
| 申请人 |
PHARMA MAR, S.A. |
发明人 |
MANZANARES, IGNACIO;MARTIN, MARIA JESUS;RODRIGUES, ALBERTO;MUNT, SIMON;CUEVAS, CARMEN;PEREZ, MARTA |
| 分类号 |
C07D471/18;C07D515/22;A61K;A61K31/4995;A61K35/00;A61P31/04;A61P35/00;C07D;C07D221/00;C07D241/00;C07D291/00;C07D317/00;C07D471/22;C07D487/18;C07D491/22;C07D497/22;C07D515/00 |
主分类号 |
C07D471/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
