| 发明名称 |
Immunomodulation by genetic modification of dendritic cells and B cells |
| 摘要 |
The present invention provides a CD40-targeted gene delivery system and a CD40-targeted recombinant adenoviral vector for genetic manipulation of dendritic cells and B cells. Also provided are methods of using this enhanced gene delivery to immune system cells and therefore, enhancing dendritic cell-based immunotherapy.
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| 申请公布号 |
US6841540(B1) |
申请公布日期 |
2005.01.11 |
| 申请号 |
US20000591737 |
申请日期 |
2000.06.12 |
| 申请人 |
THE UAB RESEARCH FOUNDATION |
发明人 |
CURIEL DAVID T.;TILLMAN BRYAN WALTER |
| 分类号 |
A61K48/00;C07K16/08;C07K16/28;C12N5/0781;C12N5/0784;C12N15/861;(IPC1-7):A61K21/70;C12N15/74;C12N5/06;C07H21/02 |
主分类号 |
A61K48/00 |
| 代理机构 |
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