发明名称 NOVEL PURINE DERIVATIVES, PREPARATION METHOD THEREOF, APPLICATION OF SAME AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE
摘要 The invention relates to novel products having formula (I), wherein: Y represents N, O, S, CHR3 or =CR3; the dotted lines represent a single or double bond; R and R1 represent, in particular, H, Hal, OH, alkyl, alkoxy, cyano, NO2, NR4R5, trifluoromethyl, trifluoromethoxy, aryl, heteroaryl, -S(O)n-NR4R5, whereby n represents 0 to 2, acyl, -NH-CO-alkyl or -NH-CO-NH-phenyl; R3 represents H, Hal, alkyl, cyano, NO2, NR4R5, trifluoromethyl or aryl; R2 represents R4, OR4, SR4 or NR4R5; and R4 represents H, alkyl, cycloalkyl or aryl. According to the invention, either R4 and R5 are selected from among the values of R4, or R4 and R5, together with N, form a heterocyclic radical which can contain N, 0 and S, all of said radicals being optionally substituted. Moreover, the aforementioned products take all of the isomeric and salt forms for use as medicaments.
申请公布号 WO2004073595(A3) 申请公布日期 2005.01.06
申请号 WO2004FR00330 申请日期 2004.02.13
申请人 AVENTIS PHARMA S.A.;BORDON-PALLIER, FLORENCE;HAESSLEIN, JEAN-LUC 发明人 BORDON-PALLIER, FLORENCE;HAESSLEIN, JEAN-LUC
分类号 A61P17/06;A61P25/28;A61P25/34;A61P31/10;A61P35/00;A61P37/00;C07D473/16 主分类号 A61P17/06
代理机构 代理人
主权项
地址