Described herein are methods of treating degenerative disc disease by injecting an antagonist such as a high specificity cytokine antagonist, a hi gh affinity antagonist of MMPs, a high specific p38 kinase inhibitor, and a cycline compound into a diseased intervertebral disc.
申请公布号
CA2525928(A1)
申请公布日期
2005.01.06
申请号
CA20042525928
申请日期
2004.05.13
申请人
DEPUY SPINE, INC.
发明人
SERHAN, HASSAN;SMITH, CATHERINE;BRUDER, SCOTT;GEESIN, JEFF;ATTAWIA, MOHAMED;KADIYALA, SUDHAKAR;COLLINS, GREGORY;PLOUHAR, PAMELA L.;SIEKIERKA, JOHN;URBAHNS, DAVID;BROWN, LAURA J.;GRACE, MELISSA;DIMAURO, THOMAS M.