A novel collagen mimic comprising a tripeptide unit having the formula (flpYaaGly)n, where flp is 4(S)-fluoro-L-proline, is disclosed. The collagen mimic has increased stability relative to the collagen-related triple helices (ProYaaGly)n, (hypYaaGly)n, and (HypYaaGly)n.
申请公布号
WO2005000872(A2)
申请公布日期
2005.01.06
申请号
WO2004US20046
申请日期
2004.06.23
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;RAINES, RONALD, T.;MITCHELL, JULIE, C.