Thermostable uvra, uvrb, and uvrc polypeptides and methods of use

摘要

The present invention provides thermostabile UvrA, UvrB and UvrC polypeptides and the polynucleotides that encode the polypeptides of the present invention. The invention also includes compositions and kits containing the UvrA, UvrB, and UvrC polypeptides of the present invention. Also provided by the invention are methods of detecting DNA damage using the UvrA and UvrB polypeptides and methods of incising DNA using the UvrA, UvrB and UvrC polypeptides of the present invention.