| 发明名称 |
Pyrazole compounds as integrin receptor antagonists derivatives |
| 摘要 |
The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the alphaVbeta3 and/or the alphaVbeta5 integrin without significantly inhibiting the alphaVbeta6 integrin.
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| 申请公布号 |
US2005004200(A1) |
申请公布日期 |
2005.01.06 |
| 申请号 |
US20030741860 |
申请日期 |
2003.12.19 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
PENNING THOMAS D.;KHILEVICH ALBERT;CHEN BARBARA B.;GANDHI PREETE;WANG YAPING;DOWNS VICTORIA L.;BOYS MARK L.;RUSSELL MARK;SPANGLER DALE P.;HUFF RENEE M. |
| 分类号 |
A61K31/415;A61K31/416;C07D401/14;C07D405/14;C07D471/04;(IPC1-7):A61K31/416;C0745/02 |
主分类号 |
A61K31/415 |
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