| 摘要 |
The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula, a pharmacologically acceptable salt thereof or hydrates thereof. Wherein A, B and D are the same as or different from each other and each represents a group represented by the formula -(CR<1>R<2>)m- (wherein R<1 >and R<2 >are the same as or different from each other and each represents a C1-6 alkyl group etc.), -NR<3>- (wherein R<3 >represetns hydrogen etc.) etc.; E and G are the same as or different from each other and each represents a group represented by the formula -(CR<6>R<7>)p- (wherein R<6 >and R<7 >are the same as or different from each other and each represents hydrogen etc.; and p represents an integer of 0, 1 or 2); J represents a carbon atom or nitrogen atom, each substituted with C1-6 alkyl group optionally substituted with a halogen atom, etc.; K and L are the same as or different from each other and each represents carbon atom or nitrogen atom; M means hydrogen, a halogen atom, an optionally substituted C1-6 alkyl group etc.; and the partial structure means a single or double bond.
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