Compounds, compositions and methods are provided for modulating the expression of apolipoprotein(a). The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein(a). Methods of using these compounds for modulation of apolipoprotein(a) expression and for diagnosis and treatment of disease associated with expression of apolipoprotein(a) are provided.
申请公布号
WO2005000201(A2)
申请公布日期
2005.01.06
申请号
WO2004US14540
申请日期
2004.06.02
申请人
ISIS PHARMACEUTICALS, INC.;CROOKE, ROSANNE, M.;GRAHAM, MARK, J.