发明名称 CD20-SPECIFIC ANTIBODIES AND METHODS OF EMPLOYING SAME
摘要 The present invention provides monoclonal antibodies and antigen-binding fragments thereof that specifically bind to CD20, as well as pharmaceutical compositions comprising the same. The invention further provides methods of using the monoclonal antibodies, antigen-binding fragments, and pharmaceutic al compositions, for example, in methods of depleting B cells or in treating B cell disorders. Also provided are cells, nucleic acids and methods for producing the monoclonal antibodies.
申请公布号 CA2525251(A1) 申请公布日期 2005.01.06
申请号 CA20042525251 申请日期 2004.05.07
申请人 DUKE UNIVERSITY 发明人 HAMAGUCHI, YASUHITO;UCHIDA, JUNJI;TEDDER, THOMAS F.;POE, JONATHAN C.
分类号 C07K16/30;A61K39/395;C07K16/28;C12N5/20;C12N15/13 主分类号 C07K16/30
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