发明名称 |
CD20-SPECIFIC ANTIBODIES AND METHODS OF EMPLOYING SAME |
摘要 |
The present invention provides monoclonal antibodies and antigen-binding fragments thereof that specifically bind to CD20, as well as pharmaceutical compositions comprising the same. The invention further provides methods of using the monoclonal antibodies, antigen-binding fragments, and pharmaceutic al compositions, for example, in methods of depleting B cells or in treating B cell disorders. Also provided are cells, nucleic acids and methods for producing the monoclonal antibodies. |
申请公布号 |
CA2525251(A1) |
申请公布日期 |
2005.01.06 |
申请号 |
CA20042525251 |
申请日期 |
2004.05.07 |
申请人 |
DUKE UNIVERSITY |
发明人 |
HAMAGUCHI, YASUHITO;UCHIDA, JUNJI;TEDDER, THOMAS F.;POE, JONATHAN C. |
分类号 |
C07K16/30;A61K39/395;C07K16/28;C12N5/20;C12N15/13 |
主分类号 |
C07K16/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|