| 摘要 |
Cpds of formula (I) and their salts: (where R'1, R" are 1-6C opt. branched alkyl or together with the N atom form a 5- or 6-membered ring R1-R10 are each H, 1-6C opt. branched alkyl, 2-3C alkenyl, hydroxy, 1-4C alkoxy (2 adjacent gps together may form a 5 or 6-membered heterocyclic ring withone or two heteroatoms), benzyloxy or halo) are diuretics and saluretics which cause less potassium excretion than known cpds. Pharmacological tests comparing their activity with 2,4,7-triamino-6-phenyl pteridine and 6-chloro-3,4-dihydro,7-sulphanmoyl-2H-1,2,4-benzothiadiazine-1,1-- dioxide. (I) may be administered orally or parenterally with the usual vehicles. |
