发明名称 |
AFFINITY SELECTION OF LIGANDS BY MASS SPECTROSCOPY |
摘要 |
Compounds are quickly selected from a combinatorial library by contacting th e library with a target (e.g., receptor), separating non-binding compounds from compound-target complexes, and analyzing the complexes or eluted compound by mass spectroscopy. SAR information is obtained by performing this selection at two or more differen t ratios of compound to target.
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申请公布号 |
CA2209988(C) |
申请公布日期 |
2005.01.04 |
申请号 |
CA19962209988 |
申请日期 |
1996.01.16 |
申请人 |
CHIRON CORPORATION |
发明人 |
HUEBNER, VERENA D.;DOLLINGER, GAVIN D.;KAUR, SURINDER |
分类号 |
G01N33/532;G01N33/53;G01N33/536;G01N33/538;(IPC1-7):G01N33/53;H01J49/26 |
主分类号 |
G01N33/532 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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