发明名称 |
Intermediates for the production of citalopram |
摘要 |
<p>Citalopram can be industrially and economically produced and at a high yield by reacting a compound of the following formula ÄVIÜ with 3-(dimethylamino)propyl chloride in the presence of at least one of N,N,N',N'-tetramethylethylenediamine and 1,3-dimethyl-2-imidazolidinone and a condensing agent. The compound of the following formula ÄIIIÜ, which is a key compound for the production of citalopram, can be easily produced by subjecting the compound of the following formula ÄIIÜ to reduction and cyclization. <CHEM></p> |
申请公布号 |
SI1125907(T1) |
申请公布日期 |
2004.12.31 |
申请号 |
SI20000030487T |
申请日期 |
2000.09.06 |
申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
IKEMOTO TETSUYA;GAO WEI-GUO;ARAI NOBUHIRO;IGI MASAMI |
分类号 |
C07C29/40;C07C33/46;C07C51/265;C07C51/373;C07C65/34;C07D307/87;(IPC1-7):C07C33/46 |
主分类号 |
C07C29/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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