发明名称 |
5-hydroxyindoles with N-oxide groups and the use thereof as therapeutic agents |
摘要 |
The invention relates to substituted 5-hydroxyindoles with N-oxide groups, processes for their preparation, pharmaceutical preparations which comprise these compounds, and the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active ingredients for the treatment of disorders which can be influenced by inhibition of phosphodiesterase 4 activity in particular in immunocompetent cells (e.g. macrophages and lymphocytes) by the compounds of the invention.
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申请公布号 |
US2004266760(A1) |
申请公布日期 |
2004.12.30 |
申请号 |
US20040824342 |
申请日期 |
2004.04.14 |
申请人 |
HOFGEN NOBERT;KUSS HILDEGARD;STEINIKE KARIN;EGERLAND UTE;RUNDFELDT CHRIS;PFEIFER THOMAS |
发明人 |
HOFGEN NOBERT;KUSS HILDEGARD;STEINIKE KARIN;EGERLAND UTE;RUNDFELDT CHRIS;PFEIFER THOMAS |
分类号 |
C07D401/12;(IPC1-7):A61K31/541;A61K31/537;A61K31/496;A61K31/443;C07D417/14;C07D413/14;C0743/02 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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