发明名称 |
Production methods of epoxytriazole derivative and intermediate therefor |
摘要 |
An epoxytriazole derivative (V) useful as an intermediate for anti-fungal agents and an intermediate therefor having high quality can be produced economically and efficiently by the following industrial means. A compound of the following formula (I) is reacted with trimethyloxosulfonium salt and the like in the presence of a base to give compound (II), this compound is converted to compound (IV), and this compound is reacted with 1,2,4-triazole in the presence of a base. wherein Ar is a phenyl group optionally substituted by 1 to 3 halogen atom(s) or trifluoromethyl group, R is a hydrogen atom or lower alkyl group, and X is a leaving group.
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申请公布号 |
US2004267024(A1) |
申请公布日期 |
2004.12.30 |
申请号 |
US20040842600 |
申请日期 |
2004.05.10 |
申请人 |
SUMIKA FINE CHEMICALS CO., LTD. |
发明人 |
WANG WEIQI;IKEMOTO TETSUYA |
分类号 |
C07C45/67;C07D249/08;C07D257/02;C07D301/02;C07D303/14;C07D303/16;C07D405/06;C07D521/00;(IPC1-7):C07D257/02 |
主分类号 |
C07C45/67 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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