| 摘要 |
A compound selected from those of formula (I): wherein: X and Y represent a group selected from hydrogen, halogen, hydroxy, alkoxy, nitro, cyano, alkyl, trihaloalkyl and NRaRb, wherein Ra and Rb are as defined in the description R1 represents hydrogen or alkyl R2 represents a group selected from hydrogen, alkyl, -OR''a, -NR'aR'b, -Ta-O''a, -N''a-Ta-NR'aR'b, -N''a-C(O)-TaH, -O-C(O) TaH, Ta-NR'aR'b, -NR''a-Ta-OR''a, -NR''a-Ta-CO2R''a and -N''a-C(O)-Ta-NR'aR'b, wherein R'a, R''a, R'b and Ta are as defined in the description R3 and R4 represent hydrogen or alkyl A represents a group of formula -CH(R5)CH(R6), -CH=C(R7)-, -C(R7)=CH-, -C(O)CH(R8) or -CH(R8)-C(O), wherein R5, R6, R7 and R8 are as defined in the description its isomers, N-oxides, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer.
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