发明名称 Antifungal 4-substituted 5,6-dihydro-4h-pyrrolo[1,2-a][1,4] benzodiazepines
摘要 The present invention concerns compounds for use as a medicine having the formula (I), the N-oxide forms, the salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R<1 >represents hydrogen, C1-6 alkyl, C1-4alkylthio, C1-4alkyloxy, or halo; R<2 >represents hydrogen or C1-6alkyl; R<3 >represents phenyl substituted with halo, cyano, C1-4alkyloxy, C1-4alkylthio, C1-6alkyl, haloC1-6alkyl; 2-thienyl; or 3-thienyl, R<4 >represents hydrogen; or R<2 >and R<4 >form an extra bond, which are active against dermatophytes, and their preparation; it further relates to compositions comprising them, as well as their use as a medicine.
申请公布号 US2004266756(A1) 申请公布日期 2004.12.30
申请号 US20040399596 申请日期 2004.02.04
申请人 GILKERSON TERENCE;NASH ROGER JOHN;VAN GESTEL JOSEF FRANS ELISABETHA;MEERPOEL LIEVEN 发明人 GILKERSON TERENCE;NASH ROGER JOHN;VAN GESTEL JOSEF FRANS ELISABETHA;MEERPOEL LIEVEN
分类号 A61K31/55;A61K31/551;A61K31/5517;A61P31/04;A61P31/10;C07D487/04;(IPC1-7):A61K31/551 主分类号 A61K31/55
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