| 摘要 |
<p>Glioblastoma remedies comprise an alpha-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) receptor antagonist. ACTIVITY : Cytostatic. In tests on nude mice implanted with CGNH-89 cells administration of [7-(1H-imidazol-1-yl)-6-nitro-2,3-dioxo-3,4-dihydroquinoxalin-1(2H)-yl] acetic acid (Ia) monohydrate at 100 mg/kg for 14 days significantly reduced tumor volume (p is less than 0.001) from day 12-20. MECHANISM OF ACTION : AMPA-Antagonist.</p> |
