发明名称 Process and coating apparatus for producing a microarray
摘要 <p>For each individual surface region (6) an absorbent substrate (15) is prepared and filled with an aqueous solution (16). Each substrate is then brought into contact with the surface region (6), in order to print it with the coating material contained in the solution. The surface of the e.g. slide (2) is structured with hydrophilic areas (6) for the substrates, divided by hydrophobic regions (7). For surface structuring, a hydrophilic layer is applied to the slide. This is coated with a photosensitive lacquer (8). This is suitably masked and exposed, and then removed from the regions to be made hydrophobic. Onto this exposed layer, the hydrophobic layer is coated. Remaining lacquer regions are then removed by etching, re-exposing the hydrophilic regions below. Various methods of construction are detailed, e.g. introduction of openings in the slide, which are then filled with the substrate, which projects. The contacting and printing process is then carried out. The openings may be filled with a mixture or monomer for introduction of the substrates. This is then polymerized and preferably cross-linked. A polymerization initiator is used. Vacuum induces materials into the openings. An independent claim is included for corresponding equipment.</p>
申请公布号 EP1491254(A2) 申请公布日期 2004.12.29
申请号 EP20040014426 申请日期 2004.06.19
申请人 MICRONAS GMBH;MICRONAS HOLDING GMBH 发明人 LEHMANN, MIRKO, DR.;KLAPPROTH HOLGER DR
分类号 B01J19/00;B01L3/00;B01L3/02;C40B60/14;(IPC1-7):B01J19/00 主分类号 B01J19/00
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