| 发明名称 |
N-[(SUBSTITUTED FIVE-MEMBERED DI- OR TRIAZA DIUNSATURATED RING)CARBONYL]GUANIDINE DERIVATIVES FOR THE TREATMENT OF ISCHEMIA |
| 摘要 |
<p>This invention relates to NHE-1 inhibitors, methods of using such NHE-1 inhibitors and pharmaceutical compositions containing such NHE-1 inhibitors. The NHE-1 inhibitors are useful for the reduction of tissue damage resulting from tissue ischemia.</p> |
| 申请公布号 |
EP1056729(B1) |
申请公布日期 |
2004.12.29 |
| 申请号 |
EP19990901083 |
申请日期 |
1999.02.05 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
HAMANAKA, ERNEST, S.;GUZMAN-PEREZ, ANGEL;RUGGERI, ROGER, B.;WESTER, RONALD, T.;MULARSKI, CHRISTIAN, J. |
| 分类号 |
C07D249/04;A61K31/41;A61K31/415;A61K31/4155;A61K31/416;A61K31/4184;A61K31/4192;A61K31/4196;A61K31/425;A61K31/428;A61K31/433;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/47;A61K31/4709;A61K31/4725;A61K31/475;A61K31/495;A61K31/498;A61K31/502;A61K31/517;A61P3/10;A61P9/00;A61P9/06;A61P9/10;A61P9/12;A61P13/12;A61P19/04;A61P35/00;A61P41/00;A61P43/00;C07D231/14;C07D231/56;C07D249/06;C07D249/10;C07D401/04;C07D403/04;C07D403/10;C07D405/04;C07D409/04;C07D413/04;C07D417/04;C07D521/00;(IPC1-7):C07D249/06 |
主分类号 |
C07D249/04 |
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