| 发明名称 |
CHOLESTEROL LOWERING BENZO[B]THIOPHENES AND BENZO[D]ISOTHIAZOLES |
| 摘要 |
<p>The present invention relates to heteroaromate OSC inhibitors. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and/or hyperproliferative disorders, and treatment and/or prophylaxis of impaired glucose tolerance and diabetes.</p> |
| 申请公布号 |
EP1334094(B1) |
申请公布日期 |
2004.12.29 |
| 申请号 |
EP20010982445 |
申请日期 |
2001.10.26 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
AEBI, JOHANNES;ACKERMANN, JEAN;DEHMLOW, HENRIETTA;MAERKI, HANS-PETER;MORAND, OLIVIER |
| 分类号 |
A61K31/381;A61K31/397;A61K31/428;A61K31/454;A61K31/496;A61K31/506;A61K31/5377;A61P3/00;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P13/12;A61P31/10;A61P33/00;A61P35/00;C07D275/04;C07D275/06;C07D333/54;C07D409/12;C07D417/12;C07D521/00;(IPC1-7):C07D333/54 |
主分类号 |
A61K31/381 |
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