发明名称 |
use of vitamin d derivatives to enhance efficacy of cytotoxic agents |
摘要 |
<p>Vitamin D derivatives and cytotoxic agents are administered sequentially to retard tumor growth : Killing cells comprises administration of a vitamin D derivative (I) followed by administration of a cytotoxic agent (II) to a cell. ACTIVITY : Antineoplastic; Anticancer; Tumoricidal; Cytotoxic. MECHANISM OF ACTION : None given.</p> |
申请公布号 |
EP1491198(A1) |
申请公布日期 |
2004.12.29 |
申请号 |
EP20040014012 |
申请日期 |
1998.08.27 |
申请人 |
UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
JOHNSON, CANDACE S.;TRUMP, DONALD |
分类号 |
A61K45/00;A61K31/282;A61K31/337;A61K31/59;A61K31/593;A61K31/675;A61K33/24;A61K45/06;A61P35/00;A61P43/00;(IPC1-7):A61K31/59 |
主分类号 |
A61K45/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|