Method of optical resolution of (+/-)-2-amino-1-butanol and/or (+/-)-mandelic acid

摘要

(+/-)-2-Amino-1-butanol and/or (+/-)-mandelic acid are optically resolved with a high resolution efficiency and high optical purities by preferentially crystallizing out one of the pair of less soluble enantiomeric salts (or optical antipodes), namely (+)-2-amino-1-butanol-(+)-mandelic acid salt and (-)-2-amino-1-butanol-(-)-mandelic acid salt.