发明名称 |
CANCEROUS DISEASE MODIFYING ANTIBODIES |
摘要 |
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodi es for therapeutic and diagnostic purposes. The antibodies can be used in aid o f staging and diagnosis of a cancer, and can be used to treat primary tumors a nd tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.
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申请公布号 |
CA2530214(A1) |
申请公布日期 |
2004.12.29 |
申请号 |
CA20042530214 |
申请日期 |
2004.06.08 |
申请人 |
ARIUS RESEARCH, INC. |
发明人 |
FINDLAY, HELEN P.;YOUNG, DAVID S. F.;HAHN, SUSAN E.;TAKAHASHI, MIYOKO |
分类号 |
A61K39/395;A61K49/00;C07K16/00;C07K16/28;C07K16/30;G01N33/569;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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