发明名称 |
Impedance measurements for detecting pathogens attached to antibodies |
摘要 |
The use of impedance measurements to detect the presence of pathogens attached to antibody-coated beads. In a fluidic device antibodies are immobilized on a surface of a patterned interdigitated electrode. Pathogens in a sample fluid streaming past the electrode attach to the immobilized antibodies, which produces a change in impedance between two adjacent electrodes, which impedance change is measured and used to detect the presence of a pathogen. To amplify the signal, beads coated with antibodies are introduced and the beads would stick to the pathogen causing a greater change in impedance between the two adjacent electrodes.
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申请公布号 |
US6835552(B2) |
申请公布日期 |
2004.12.28 |
申请号 |
US20000737542 |
申请日期 |
2000.12.14 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MILES ROBIN R.;VENKATESWARAN KODUMUDI S.;FULLER CHRISTOPHER K. |
分类号 |
G01N27/02;G01N33/543;(IPC1-7):G01N33/53 |
主分类号 |
G01N27/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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