| 摘要 |
Compounds according to general formula (1) and their pharmaceutically acceptable salts are new. The compounds are inhibitors of dipeptidyl peptidase IV or prodrugs thereof, and are useful in the treatment of, inter alia type 2 diabetes and impaired glucose tolerance. In the general formula A is F or H, one of R<1A >and R<1B >is H or CN and the other H, R<2 >is H, alkyl, aralkyl or R<5>, R<3 >is H or a substituted aminoalkyl group and R<4 >is H or acyl. |
