| 摘要 |
This application is directed to compounds of the formulawherein j is 1; k is 0 or 1; m is 1, 2 or 3; n is 1 or 2; W<1 >and W<2 >are independently -O- or -S(=O)t-, where t is 0, 1, or 2; Y is =C(R<1>a)-, where R<1>a is a member selected from the group consisting of H; F; Cl; CN; NO2; -(C1-C4) alkyl; -(C2-C4) alkynyl; fluorinated-(C1-C3) alkyl; fluorinated-(C1-C3) alkoxy; -OR<16>; and -C(=O)NR<22>aR<22>b; R<22>a and R<22>b are defined as set forth in the specification; -R<A >and R<B >are each a member independently selected from the group consisting of H; F; CF3; -(C1-C4) alkyl; -(C3-C7) cycloalkyl; phenyl; and benzyl; wherein said cycloalkyl, phenyl, and benzyl moieties are each independently substituted with 0 to 3 substituents R<10>, which is defined as set forth in the specification; R<16 >and R<17 >are defined as set forth in the specification; -R<C >and R<D >have the same meaning as defined above for R<A >and R<B >except that one of them must be -H, and they are selected independently of each other and of R<A >and R<B>; R<1 >and R<2 >are each a member independently selected from the group consisting of H; F; Cl; CN; NO2; -(C1-C4) alkyl; -(C2-C4) alkynyl; fluorinated-(C1-C3)alkyl; OR<16>; and -C(=O)NR<22>aR<22>b; -R<3 >is H; -(C1-C3)alkyl; phenyl; benzyl; or OR<16>; R<4>, R<5 >and R<6 >are defi |
