| 发明名称 |
PROCESS FOR THE PREPARATION OF 9-AMINO SUBSTITUTED 9,10-DIHYDROPYRROLO [2,1-B][1,3]BENZOTIAZEPINES |
| 摘要 |
A process is described for the preparation of compounds with the following formula where the groups are as defined below; in particular, R<SUB>1 </SUB>is a substituted amine; said process includes essentially the reaction of pyrrolobenzothiazepin-9-one with amine R<SUB>1</SUB>H to give the corresponding enamine, which is subsequently transformed into the final compound |
| 申请公布号 |
PL365009(A1) |
申请公布日期 |
2004.12.27 |
| 申请号 |
PL20010365009 |
申请日期 |
2001.07.20 |
| 申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA. |
发明人 |
MINETTI PATRIZIA;MASTROIANNI DOMENICO |
| 分类号 |
A61K31/216;A61K31/554;A61P25/00;C07B61/00;C07D;C07D209/00;C07D281/00;C07D498/02;C07D513/04 |
主分类号 |
A61K31/216 |
| 代理机构 |
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代理人 |
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