发明名称 HETEROARYL-SUBSTITUTED IMDAZOLE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS
摘要 <p>The present invention relates to imidazole derivatives of the general formula (I) wherein R<1>, R<2>, R<3> and R<4> are as defined in the specification as well as to pharmaceutically acceptable salts thereof and to processes for the preparation thereof. The invention also relates to the use of said imidazole derivatives for the preparation of medicaments and to medicaments containing them for the prevention or the treatment of mGluR5 receptor mediated disorders, such as acute and/or chronic neurological disorders, in particular anxiety, or for the treatment of chronic and acute pain.</p>
申请公布号 WO2004111040(A1) 申请公布日期 2004.12.23
申请号 WO2004EP06111 申请日期 2004.06.07
申请人 F. HOFFMANN-LA ROCHE AG;BUETTELMANN, BERND;CECCARELLI, SIMONA, MARIA;JAESCHKE, GEORG;KOLCZEWSKI, SABINE;PORTER, RICHARD, HUGH, PHILIP;VIEIRA, ERIC 发明人 BUETTELMANN, BERND;CECCARELLI, SIMONA, MARIA;JAESCHKE, GEORG;KOLCZEWSKI, SABINE;PORTER, RICHARD, HUGH, PHILIP;VIEIRA, ERIC
分类号 A61P25/28;C07D233/54;C07D401/04;C07D403/04;C07D405/04;C07D417/14;(IPC1-7):C07D403/04;A61K31/443;A61K31/496;A61K31/497 主分类号 A61P25/28
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