发明名称 FUSED INDOLES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
摘要 The present invention is directed to fused indole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularl y type 2 diabetes. The invention is also directed to pharmaceutical compositio ns comprising these compounds and the use of these compounds and compositions i n the prevention or treatment of such diseases in which the dipeptidyl peptida se- IV enzyme is involved.
申请公布号 CA2526770(A1) 申请公布日期 2004.12.23
申请号 CA20042526770 申请日期 2004.06.02
申请人 MERCK & CO., INC. 发明人 EDMONDSON, SCOTT D.;PARMEE, EMMA R.;MASTRACCHIO, ANTHONY
分类号 A61K31/403;A61K31/427;C07D209/86;C07D209/88;C07D403/06;C07D417/06 主分类号 A61K31/403
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