发明名称 |
Kit for delivering decitabine in vivo |
摘要 |
Pharmaceutical formulations, kits and vessels are provided for delivering decitabine to a patient suffering from a disease in need of treatment with decitabine. The pharmaceutical formulation comprises decitabine solvated in a non-aqueous solvent that comprises glycerin, propylene glycol, polyethylene glycol, or combinations. Such formulations are more chemically stable than conventional liquid formulations of decitabine containing more than 40% water in volume. The pharmaceutical formulations can be used for any disease that is sensitive to the treatment with decitabine, such as hematological disorders and cancer.
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申请公布号 |
US2004259820(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
US20040890621 |
申请日期 |
2004.07.13 |
申请人 |
JOSHI-HANGAL RAJASHREE;ZHANG XICHEN;GONG STEPHANIE;REDKAR SANJEEV;GORE ASHOK Y. |
发明人 |
JOSHI-HANGAL RAJASHREE;ZHANG XICHEN;GONG STEPHANIE;REDKAR SANJEEV;GORE ASHOK Y. |
分类号 |
A61K9/08;A61K9/00;A61K9/14;A61K9/19;A61K31/706;A61K31/7072;A61K45/00;A61K47/02;A61K47/10;A61K47/12;A61K47/18;A61K47/20;A61K47/22;A61K47/26;A61K47/34;A61K47/36;A61K47/40;A61P1/04;A61P7/04;A61P7/06;A61P9/10;A61P17/02;A61P17/06;A61P19/02;A61P21/00;A61P25/02;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P31/22;A61P33/00;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;(IPC1-7):A61K31/707 |
主分类号 |
A61K9/08 |
代理机构 |
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