发明名称 |
Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines |
摘要 |
Composition of matter for application to a body surface or membrane to administer a N-(2,5-Disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidine by permeation through the body surface or membrane, the composition comprising the guanidine compound to be administered, at a therapeutically effective rate, optionally in combination with a permeation enhancer or mixture. Also disclosed are drug delivery devices and methods for the transdermal administration of a guanidine for the prevention of neuropathic pain, neuropsychological deficits resulting from cardiac surgery (CABG), and other neurological disorders.
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申请公布号 |
US2004258742(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
US20040895788 |
申请日期 |
2004.07.20 |
申请人 |
VAN OSDOL WILLIAM WOODSON;GALE ROBERT MARTIN;BRANDWEIN DAVID HENRY;PADMANABHAN RAMA;SUNRAM JOAN |
发明人 |
VAN OSDOL WILLIAM WOODSON;GALE ROBERT MARTIN;BRANDWEIN DAVID HENRY;PADMANABHAN RAMA;SUNRAM JOAN |
分类号 |
A61K9/70;(IPC1-7):A61K9/70;A61L15/16 |
主分类号 |
A61K9/70 |
代理机构 |
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地址 |
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