| 发明名称 |
FUSION PROTEINS |
| 摘要 |
The invention provides active therapeutic peptides fused to specific IgG4-Fc derivatives. These fusion proteins have an increased half-life, reduced half antibody formation, and reduced effector activity, while not being immunogenic. The fusion proteins are useful in treating human diseases as we ll as a variety of other conditions or disorders.
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| 申请公布号 |
CA2526169(A1) |
申请公布日期 |
2004.12.23 |
| 申请号 |
CA20042526169 |
申请日期 |
2004.06.10 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
TSCHANG, SHENG-HUNG RAINBOW;VICK, ANDREW MARK;GLAESNER, WOLFGANG;MILLICAN, ROHN LEE JR.;TIAN, YU |
| 分类号 |
A61K38/17;A61K38/00;A61P3/10;C07K14/47;C07K14/50;C07K14/605;C12N15/62 |
主分类号 |
A61K38/17 |
| 代理机构 |
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